Most of you are not familiar with vitiligo what exactly is Vitiligo Disease? Vitiligo is a chronic skin disorder in which the cells responsible for skin pigmentation are unable to function or destroyed. This results in irregular patches of skin. Similar patches also appear inside of the mouth, nose, and the retina. Some evidence suggesting it is caused by a combination of auto-immune, genetic, and environmental factors.
Also is there strong evidence that people with this disease inherit a group of three genes that make them susceptible to de-pigmentation. People who develop vitiligo usually first notice white blotches (de-pigmentation) on their body. These milky spots are more commonly found on sun-exposed areas of the body, such as hands, feet, arms, face, lips, and around eyes, mouth and nostrils. Other common areas for white marks to appear are the armpits and groin, and around the navel, genitals, and rectal areas.
Around 1% to 2% of the total population in the United States has Vitiligo disease. As of estimates, as many as 65 million people of the world population are suffering from this disorder. The most widely accepted view is that the de-pigmentation occurs because vitiligo is an autoimmune disease. Autoimmune is a disease in which a man’s immune system reacts against the body’s own organs or tissues. Once immune system gets reversed, people’s bodies produce proteins called cytokines that alter their pigment-producing cells. As a result of which these cells die.
A quarter of people believe that melanocytes destroy themselves. Half of people with Vitiligo develop blotches of de-pigmented skin appearing on extremities before they turn 20. Age of onset of this disorder is often in young adulthood. While most develop it before they celebrate their 40th birthdays. The condition tends to progress gradually with marks enlarging and extending until a quiescent state is reached. There are very explicit signs of vitiligo disorder, mainly characterized by unpigmented skin and milky white marks.
Diseases like vitiligo have little existence but vitiligo is most common now. Vitiligo does not damage the health. But it destroys the personality badly and creates psychological problems. It can come out in any age, race and in any gender.
In vitiligo disease, melanocyte cells which give our skin the color of our body lose the ability to synthesize the pigments. Occasionally small areas may lose pigment as they are recolonised by melanocytes. Vitiligo on the scalp may affect the color of the hair. The hair that grows on vitiligo affected areas sometimes turns white. It also similarly affects facial and body hair.
The People with vitiligo usually, experience a range of feelings and emotions including; shock, denial, anger, fear, embarrassed, ashamed, guilt, anxiety, isolation, depression and finally acceptance. They remain always worried about, how others people will react with them. A lot of people become overwhelmed at getting low self-esteem and due to lack of confidence.
Nevus depigmentosus is a stable disease which is limited to a small area. It appears in the form of white spots on body. It increases as the growth of body increases. The main cause of this disease is the irregularity in the function of melanocytes which produce little pigments.
White scars and hypopigmentation is another skin disease which looks like vitiligo. In this disease scars appear due to injury. Scars may be white or colored; it depends on type of injury. Scars can be a result of physical, chemical or inflammatory as acne. Melanocytes may destroy or damage due to injury. Therefore white scars and hypopigmentation occurs.
Pityriases Alba is also a skin disease which is frequently present in children. It mostly comes into views in dry weather and the people having dry skin. It generally appears as dry scales, pale patches on the face. Normally, boys are affected by this disease. It takes place due to activity of melanocytes abnormally low.
Idiopathic guttate hypomelanosis has also confusion with vitiligo. Generally, women suffer from this disease. It appears in the form of round shape on skin. Parts of body having exposure of sun light, experience idiopathic guttate hypomelanosis like face, forearms, shoulders. A medical treatment that involves removal of damage tissues and cells known as biopsies is used to treat that problem but as a result thickness of skin reduces. Protection from the sun is very important in this disease. It is commonly observed in people having fair complexion.